soluble guanylate cyclase

Soluble guanylate cyclase and NO/cGMP signalling in vascular disease



NO-independent stimulators and activators of soluble guanylate cyclase:



Cellular cyclic GMP is increased by activation of soluble guanylate cyclase



Soluble and Particulate Guanylyl Cyclase



The heterodimeric soluble guanylyl cyclase consists of a heme domain,



Marletta Lab - Soluble Guanylate Cyclase



Catalysis of cyclic GMP synthesis by soluble guanylyl cyclase.



Figure 1: Schematic presentation of the soluble guanylate cyclase screening



Soluble guanylate cyclase (sGC) catalyzes the conversion of GTP to the



Soluble guanylyl cyclase (sGC) is a cytosolic signaling enzyme closely



b) soluble guanylate cyclase



of the NO binding heme domain of the soluble guanylyl cyclase receptor.



NO-independent stimulators and activators of soluble guanylate cyclase:



GTP (Guanosine 5`-triphosphate), sGC (Soluble guanylate cyclase).



Tonic and acute nitric oxide signaling through soluble guanylate cyclase is



GTP (Guanosine 5`-triphosphate), sGC (Soluble guanylate cyclase).



Inhibition of soluble guanylate cyclase prevents the AQP1 conductance response to SNP



Revisiting the kinetics of nitric oxide (NO) binding to soluble guanylate



nuclear factor-κB; NO, nitric oxide; sGC, soluble guanylate cyclase.



Effect of Soluble Guanylate Cyclase-Specific Inhibitor on Tissue Relaxation